Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PP_4978Homologs of previously reported genes of unknown function. (361 aa)    
Predicted Functional Partners:
metF
5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Biosynthesisofcofactors,prostheticgroups,andcarriers : Folic acid; Belongs to the methylenetetrahydrofolate reductase family.
  
    0.829
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
    0.548
PP_3142
Putative Sugar transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.505
PP_4979
Putative Periplasmic binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
       0.461
PP_4638
Methylenetetrahydrofolate reductase.
  
    0.455
rhlE-II
ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
       0.453
PP_3016
Putative Lipopolysaccharide core biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
  
 0.405
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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