STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilIProtein PilI. (184 aa)    
Predicted Functional Partners:
PP_4988
Signal transduction histidine kinase CheA/CheY-like receiver; Function of strongly homologous gene; enzyme; Signaltransduction : Two-component systems.
 
 0.999
PP_4987
Putative Chemotaxis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
 
 
 0.996
pilJ
Protein PilJ.
 
 0.994
pilH
Protein PilH.
 
 
 0.993
pilG
Protein PilG.
 
 
 0.990
PP_1492
Sensor histidine kinase/response regulator.
 
 
 0.965
cheA
Chemotaxis histidine kinase CheA.
 
 
 0.963
PP_2310
Methyl-accepting chemotaxis transducer.
 
 
 0.857
mcpQ
Putative methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpQ recognizes specifically citrate and citrate/metal(2+) complexes. Binds citrate/metal(2+) complexes with higher affinity than free citrate, and mediates preferentially chemotaxis toward citrate/metal(2+) complexes.
 
 
 0.857
mcpS
Putative methyl-accepting chemotaxis protein; Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. McpS is a specific chemoreceptor for 6 tricarboxylic acid (TCA) cycle intermediates (succinate, fumarate, malate, oxaloacetate, citrate and isocitrate), butyrate and acetate. Malate, succinate, fumarate and oxaloacetate cause the strongest chemotactic response.
 
 
 0.856
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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