Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PP_4995Putative protein possibly involved in the control of exopolysaccharide production; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Biologicalprocesses : Control; Belongs to the UPF0301 (AlgH) family. (189 aa)    
Predicted Functional Partners:
PP_4996
Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family.
  
  
 0.973
nrdA
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 0.951
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
    0.841
pyrR
Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase; Function of strongly homologous gene; regulator.
  
    0.793
gshB
Glutathione synthetase.
 
   
 0.791
pyrC-2
Dihydroorotase-like protein; Function experimentally demonstrated in the studied species; enzyme.
  
    0.783
rseP
Regulatory intramembrane protein RIP zinc protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Regulatoryfunctions : Protein interactions.
      
 0.747
PP_4994
Homologs of previously reported genes of unknown function.
  
  
 0.729
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.648
pilH
Protein PilH.
  
    0.612
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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