STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phaC-IIPoly(3-hydroxyalkanoate) polymerase 2; Function of strongly homologous gene; enzyme. (560 aa)    
Predicted Functional Partners:
phaB
Poly(3-hydroxyalkanoate) depolymerase.
 
  
 0.953
fadB
enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
     
 0.950
phaA
Poly(3-hydroxyalkanoate) polymerase 1; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
0.948
PP_5006
Transcriptional regulator, TetR family.
  
    0.767
fadD-II
long-chain-fatty-acid/CoA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.675
fadBA
3-hydroxyacyl-CoA dehydrogenase type-2; Function experimentally demonstrated in the studied species; enzyme; Fatty acid and phospholipid metabolism; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.669
aacs
Acetoacetyl-coenzyme A synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism.
   
  
 0.657
PP_0763
Medium-chain-fatty-acid CoA ligase.
      
 0.587
pcaF-I
beta-ketoadipyl-CoA thiolase; Function experimentally demonstrated in the studied strain; enzyme; Energy metabolism; Belongs to the thiolase-like superfamily. Thiolase family.
  
  
 0.508
acsA-II
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
  
 0.456
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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