Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
proYProline (histidine) APC transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Glutamate family. (467 aa)    
Predicted Functional Partners:
hutI
Imidazolonepropionase; Function experimentally demonstrated in the studied strain; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
  
  
 0.925
PP_3559
Glycine betaine ABC transporter (permease); Function of strongly homologous gene; transporter; Transportandbindingproteins : Amino acids, peptides and amines.
  
  
 0.854
hutH
Histidine ammonia-lyase; Function experimentally demonstrated in the studied strain; enzyme; Fattyacidandphospholipidmetabolism : Degradation; Belongs to the PAL/histidase family.
  
  
 0.832
hutG
N-formylglutamate deformylase; Function experimentally demonstrated in the studied strain; enzyme; Fattyacidandphospholipidmetabolism : Degradation.
  
    0.827
PP_3558
Putative Amino acid transporter, periplasmic amino acid-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  
 0.783
proP
Osmosensory proline/betaine/H+ permease; Function of homologous gene experimentally demonstrated in an other organism; transporter; Aminoacidbiosynthesis : Glutamate family.
      
 0.695
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
  
  
 0.680
pip
Proline iminopeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase S33 family.
     
 0.648
dtd
D-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
       0.571
hutF
Probable formiminoglutamate deiminase; Function experimentally demonstrated in the studied strain; putative enzyme; Fattyacidandphospholipidmetabolism : Degradation.
  
  
 0.568
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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