STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbpFructose-1,6-bisphosphatase, class 1; Function of strongly homologous gene; enzyme; Energymetabolism : Glycolysis/gluconeogenesis. (336 aa)    
Predicted Functional Partners:
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
 
 0.984
fruK
1-phosphofructokinase monomer; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the carbohydrate kinase PfkB family.
    
 0.971
tktA
Transketolase A; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.963
pgi-I
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.955
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.945
pgi-II
Glucose-6-phosphate isomerase; Function of strongly homologous gene; enzyme.
   
 
 0.936
algA
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity).
   
 0.933
PP_1776
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
   
 0.933
PP_5039
Homologs of previously reported genes of unknown function.
  
    0.831
cra
Catabolite repressor-activator, DNA-binding transcriptional dual regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator; Energymetabolism : Entner-Doudoroff.
      
 0.777
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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