STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbpFructose-1,6-bisphosphatase, class 1; Function of strongly homologous gene; enzyme; Energymetabolism : Glycolysis/gluconeogenesis. (336 aa)    
Predicted Functional Partners:
fba
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
 
 
 0.979
pgi-I
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.975
tktA
Transketolase A; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.968
pgi-II
Glucose-6-phosphate isomerase; Function of strongly homologous gene; enzyme.
   
 
 0.960
fruK
1-phosphofructokinase monomer; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the carbohydrate kinase PfkB family.
    
 0.956
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.946
algA
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Produces a precursor for alginate polymerization. The alginate layer provides a protective barrier against host immune defenses and antibiotics (By similarity).
   
 0.921
PP_1776
Mannose-6-phosphate isomerase/mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
   
 0.921
PP_5039
Homologs of previously reported genes of unknown function.
  
    0.888
glgP
Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
   
 
 0.800
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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