| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| era | obg | PP_1434 | PP_0690 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.937 |
| era | rimP | PP_1434 | PP_4714 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosome maturation factor; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.919 |
| era | tsf | PP_1434 | PP_1592 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.731 |
| era | typA | PP_1434 | PP_5044 | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosome associated GTPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknown function. | 0.760 |
| gltB | guaA | PP_5076 | PP_1032 | L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.822 |
| gltB | thiI | PP_5076 | PP_5045 | L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.584 |
| gltB | tsf | PP_5076 | PP_1592 | L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.486 |
| gltB | typA | PP_5076 | PP_5044 | L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. | Ribosome associated GTPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknown function. | 0.699 |
| gltB | ychF | PP_5076 | PP_0719 | L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. | Ribosome-associated potassium-dependent informational ATP/GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.595 |
| guaA | gltB | PP_1032 | PP_5076 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | L-glutamate synthase(NADPH) alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family. | 0.822 |
| guaA | obg | PP_1032 | PP_0690 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.502 |
| guaA | thiI | PP_1032 | PP_5045 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.731 |
| guaA | tsf | PP_1032 | PP_1592 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.527 |
| guaA | typA | PP_1032 | PP_5044 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosome associated GTPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknown function. | 0.725 |
| guaA | ychF | PP_1032 | PP_0719 | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosome-associated potassium-dependent informational ATP/GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.677 |
| obg | era | PP_0690 | PP_1434 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.937 |
| obg | guaA | PP_0690 | PP_1032 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.502 |
| obg | rimP | PP_0690 | PP_4714 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosome maturation factor; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.682 |
| obg | tsf | PP_0690 | PP_1592 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.605 |
| obg | typA | PP_0690 | PP_5044 | GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Ribosome associated GTPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Unknown function. | 0.838 |