STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnGTwo-component system DNA-binding transcriptional dual regulator GlnL/GlnG; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (478 aa)    
Predicted Functional Partners:
glnL
Two-component system sensory histidine kinase/phosphatase GlnL/GlnG; Function of homologous gene experimentally demonstrated in an other organism; receptor; Centralintermediarymetabolism : Nitrogen metabolism.
 0.998
rpoN
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the xylCAB operon and the xylS gene. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator protein XylR for the expression of the xylCAB operon and xylS.
 
   
 0.964
glnA
Glutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family.
  
  
 0.902
glnK
Activator of NRII(GlnL/NtrB) phosphatase; Function of homologous gene experimentally demonstrated in an other organism; regulator; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the P(II) protein family.
   
 
 0.869
amtB
Ammonium transporter AmtB; Function of homologous gene experimentally demonstrated in an other organism; transporter; Transportandbindingproteins : Cations and iron carrying compounds.
   
  
 0.776
gdhA
Glutamate dehydrogenase, NADP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
  
 0.760
puuA-I
Glutamate-putrescine ligase; Function experimentally demonstrated in the studied genus; enzyme; Central intermediary metabolism; Belongs to the glutamine synthetase family.
  
  
 0.757
puuA-II
Glutamate-putrescine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Glutamate family; Belongs to the glutamine synthetase family.
  
  
 0.757
PP_4547
Putative Glutamine synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the glutamine synthetase family.
  
  
 0.756
rpoD
RNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
      
 0.754
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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