Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
grxCGlutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (84 aa)    
Predicted Functional Partners:
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.924
PP_5055
Sulfurtransferase.
  
  
 0.898
nrdA
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.829
yrfG
Purine nucleotidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.813
grxD
Monothiol glutaredoxin 4; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energymetabolism : Electron transport; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.740
trxB
Thioredoxin reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Central intermediary metabolism.
   
 
 0.703
dinG
Putative Helicase; DNA-dependent ATPase and 5'-3' DNA helicase.
      
 0.634
gpmI
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
 
     0.630
PP_3639
Alkylhydroperoxidase AhpD domain protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
     
 0.589
PP_2887
Catalase-related peroxidase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
   
 
 0.580
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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