STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
betBBetaine aldehyde dehydrogenase, NAD-dependent; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. (490 aa)    
Predicted Functional Partners:
betA-II
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
 
 0.996
betA-I
Choline dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.979
PP_5373
Rieske 2Fe-2S family protein.
   
 
 0.974
betI
Choline-responsive transcriptional repressor BetI; Repressor involved in choline regulation of the bet genes.
  
 0.935
PP_0708
Putative Betaine-aldehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.914
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.893
betT-I
Choline transporter; Function experimentally demonstrated in the studied genus; transporter; Mobileandextrachromosomalelementfunctions : Transposon functions; Belongs to the BCCT transporter (TC 2.A.15) family.
 
 
  
 0.593
yiaY
Fe-containing alcohol dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Central intermediary metabolism.
 
 
 0.546
glpF
Aquaglyceroporin; Function of homologous gene experimentally demonstrated in an other organism; transporter; Fattyacidandphospholipidmetabolism : Biosynthesis; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.497
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
      
 0.432
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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