STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
betA-IICholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (565 aa)    
Predicted Functional Partners:
betB
Betaine aldehyde dehydrogenase, NAD-dependent; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
 
 0.996
betI
Choline-responsive transcriptional repressor BetI; Repressor involved in choline regulation of the bet genes.
  
 0.983
PP_0708
Putative Betaine-aldehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the aldehyde dehydrogenase family.
  
 
 0.982
psd
Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
   
 
  0.803
PP_5373
Rieske 2Fe-2S family protein.
     
 0.788
PP_5159
Homologs of previously reported genes of unknown function.
      
 0.767
betC
Choline-sulfatase; Function experimentally demonstrated in the studied strain; enzyme; Central intermediary metabolism.
    
 0.660
PP_4630
Transcriptional regulator, MerR family.
   
  
 0.659
PP_0015
Putative transposon protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Mobileandextrachromosomalelementfunctions : Transposon functions.
      
 0.655
PP_3761
Sensor histidine kinase/response regulator.
      
 0.631
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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