Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
Score
PP_5086Putative nuclease (SNase domain protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (255 aa)    
Predicted Functional Partners:
rpmE
Ribosomal protein L31; Binds the 23S rRNA.
  
    0.797
maeB
Malic enzyme B; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.710
priA
Primosome assembly protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.701
argS
arginyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
   0.632
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.612
PP_1357
Homologs of previously reported genes of unknown function; Unknown function.
      
 0.584
PP_5090
Putative cell division protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
 
     0.557
hslV
Peptidase component of the ATP-dependent HslVU protease; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
       0.488
hslU
Protease HslVU, ATPase component; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
       0.488
PP_5002
Homologs of previously reported genes of unknown function.
       0.488
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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