Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sseAPutative 3-mercaptopyruvate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (284 aa)    
Predicted Functional Partners:
glpE
Thiosulfate sulfurtransferase GlpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
  
 0.990
PP_1703
Assimilatory nitrate reductase/sulfite reductase; Function of strongly homologous gene; enzyme; Centralintermediarymetabolism : Nitrogen metabolism; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
    
 0.980
PP_0860
Putative Sulfite reductase, flavoprotein component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
     
 0.977
PP_4594
Putative Cystathionine gamma-synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.977
cysI
Sulphite reductase hemoprotein, beta subunit.
    
 0.961
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
    
 0.945
rhdA
Thiosulfate sulfurtransferase.
  
 
 
0.926
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 
 0.925
iscS-I
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.922
iscS-II
Cysteine desulfurase; Function of strongly homologous gene; enzyme.
  
 0.916
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
Server load: medium (50%) [HD]