STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsPPhosphoenolpyruvate-dependent regulator (with NPR and NTR proteins); Function of homologous gene experimentally demonstrated in an other organism; regulator; Energy metabolism; Belongs to the PEP-utilizing enzyme family. (759 aa)    
Predicted Functional Partners:
ptsN
Phosphotransferase system enzyme IIA, regulation of potassium transport; Function of homologous gene experimentally demonstrated in an other organism; regulator; Transportandbindingproteins : Carbohydrates, organic alcohols, and acids.
  
  
 0.978
ptsH
Phosphocarrier protein HPr.
  
 
 
 0.951
fruA
Fructose PTS permease - IIBC component; Function of homologous gene experimentally demonstrated in an other organism; transporter; Energy metabolism.
  
   
 0.907
rppH
RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
  
 0.787
PP_0063
Putative Lipid A biosynthesis lauroyl acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
      
 0.703
fruB
Phosphotransferase system, fructose-specific EI/HPr/EIIA components; Function experimentally demonstrated in the studied genus; transporter; Energymetabolism : Sugars; Belongs to the PEP-utilizing enzyme family.
  
 
 
0.668
cysM
Cysteine synthase B; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Aminoacidbiosynthesis : Serine family; Belongs to the cysteine synthase/cystathionine beta- synthase family.
      
 0.649
fruK
1-phosphofructokinase monomer; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Energy metabolism; Belongs to the carbohydrate kinase PfkB family.
  
   
 0.587
pcnB
poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
   
 0.539
PP_5147
Hydrolase, haloacid dehalogenase-like family.
  
    0.521
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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