STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PP_5743Putative TonB-dependent receptor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (335 aa)    
Predicted Functional Partners:
tolA
Colicin S4 and filamentous phage transport system; Function experimentally demonstrated in the studied strain; transporter; Cellenvelope : Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides.
   
 
 0.534
PP_4994
Homologs of previously reported genes of unknown function.
   
 
 0.534
tonB
Protein TonB.
   
 
 0.534
metH
Cobalamin-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.523
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
      
 0.518
PP_3333
Homologs of previously reported genes of unknown function.
       0.511
cobJ
Precorrin-3B C17-methyltransferase.
  
  
 0.467
tolB
Component of the Tol biopolymer transport system; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
    
 
 0.461
PP_5538
Putative ABC transporter, substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Transport and binding proteins.
   
  
 0.460
PP_3492
Short-chain acyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme.
      
 0.440
Your Current Organism:
Pseudomonas putida KT2440
NCBI taxonomy Id: 160488
Other names: P. putida KT2440, Pseudomonas putida (strain KT2440), Pseudomonas putida str. KT2440
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.