STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XF_0002DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] (366 aa)    
Predicted Functional Partners:
XF_0676
DNA polymerase III, delta subunit; Similar to SP|P52024 (percent identity: 35 %/query alignment coverage: 74.2 %/subject alignment coverage: 75.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
 0.999
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.995
XF_2178
DNA polymerase III, delta subunit; Similar to SP|P28630 (percent identity: 29 %/query alignment coverage: 96.2 %/subject alignment coverage: 96.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.995
dnaE
DNA polymerase III, alpha chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase (By similarity); Belongs to the DNA polymerase type-C family. DnaE subfamily.
    
 0.994
dnaX
DNA polymerase III subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.994
dnaQ
DNA polymerase III, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
  
 0.993
dnaA
Chromosomal replication initiator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).
 
 
 0.979
mutS
Mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
  
 0.976
XF_0136
DNA polymerase III holoenzyme chi subunit; Similar to GI|2984772 (percent identity: 34 %/query alignment coverage: 101.4 %/subject alignment coverage: 100.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.973
XF_0590
Conserved hypothetical protein; Similar to SP|P76570 (percent identity: 36 %/query alignment coverage: 97.4 %/subject alignment coverage: 91.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the DnaA family. HdA subfamily.
 
 
 0.973
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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