STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (377 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
  
 0.955
dapD
2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Similar to SP|Q9ZEX2 (percent identity: 60 %/query alignment coverage: 90.0 %/subject alignment coverage: 98.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the transferase hexapeptide repeat family.
 
   
 0.943
argD
Succinylornithine aminotransferase; Similar to SP|P77581 (percent identity: 48 %/query alignment coverage: 97.3 %/subject alignment coverage: 98.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.923
XF_0115
Conserved hypothetical protein; Similar to SP|P24178 (percent identity: 42 %/query alignment coverage: 93.5 %/subject alignment coverage: 98.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the ArsC family.
  
    0.729
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
      
 0.607
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
 
 0.585
dapA
Dihydroxydipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
   
 0.553
XF_0117
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -36.
       0.545
argG
Argininosuccinate synthase; Similar to SP|Q60174 (percent identity: 36 %/query alignment coverage: 97.3 %/subject alignment coverage: 98.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.512
prmB
Adenine-specific methylase; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
 
    0.509
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: low (24%) [HD]