Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrEOrotate phosphoribosyl transferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (219 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.993
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.993
carB
Carbamoyl-phosphate synthase large chain; Similar to SP|P00968 (percent identity: 68 %/query alignment coverage: 100.0 %/subject alignment coverage: 100.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.938
pyrB
Aspartate carbamoyltransferase; Similar to SP|Q59653 (percent identity: 52 %/query alignment coverage: 96.0 %/subject alignment coverage: 92.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 51.
  
  
 0.934
prs
Phosphoribosyl pyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.891
XF_0988
Dihydroorotase; Similar to SP|O27199 (percent identity: 30 %/query alignment coverage: 96.2 %/subject alignment coverage: 95.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 0.883
carA
Carbamoyl-phosphate synthase small chain; Similar to SP|P38098 (percent identity: 68 %/query alignment coverage: 94.0 %/subject alignment coverage: 99.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the CarA family.
  
  
 0.881
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.767
purL
Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
  
 0.761
guaA
Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.697
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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