STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XF_0164Exodeoxyribonuclease; Similar to GI|6138859 (percent identity: 43 %/query alignment coverage: 103.0 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. (266 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.966
XF_1933
Exodeoxyribonuclease III; Similar to GI|1653682 (percent identity: 46 %/query alignment coverage: 100.4 %/subject alignment coverage: 96.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 
0.927
XF_0165
Beta-lactamase induction signal transducer protein; Similar to SP|P36670 (percent identity: 38 %/query alignment coverage: 55.2 %/subject alignment coverage: 57.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
       0.829
hfq
Host factor-I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
 
 0.805
XF_1796
Similar to SP|P06709 (percent identity: 40 %/query alignment coverage: 95.9 %/subject alignment coverage: 94.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
    0.768
XF_0002
DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...]
   
 0.739
XF_1909
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.730
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.610
XF_1200
Ribosomal small subunit pseudouridine synthase; Similar to SP|P33918 (percent identity: 42 %/query alignment coverage: 99.2 %/subject alignment coverage: 101.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the pseudouridine synthase RsuA family.
  
    0.576
rluB
Conserved hypothetical protein; Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; Belongs to the pseudouridine synthase RsuA family.
  
    0.576
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.