STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvHGlycine cleavage H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (144 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage T protein; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.999
gcvP
Glycine decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 
 0.999
XF_0868
Dihydrolipoamide dehydrogenase; Similar to GI|1073212 (percent identity: 57 %/query alignment coverage: 100.2 %/subject alignment coverage: 101.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
 0.994
XF_1548
Dihydrolipoamide dehydrogenase; Similar to SP|P14218 (percent identity: 58 %/query alignment coverage: 97.6 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
  
 0.985
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.968
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 
 0.925
lipB
Lipoate biosynthesis protein B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
   
 0.893
XF_2710
Glutamate synthase, alpha subunit; Similar to SP|P09831 (percent identity: 53 %/query alignment coverage: 99.7 %/subject alignment coverage: 97.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -117.
   
 
 0.889
XF_1550
Oxoglutarate dehydrogenase; Similar to SP|Q59106 (percent identity: 54 %/query alignment coverage: 97.6 %/subject alignment coverage: 99.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
   
 
 0.864
XF_1842
Glutamine synthetase; Similar to SP|P06711 (percent identity: 64 %/query alignment coverage: 92.9 %/subject alignment coverage: 99.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
   
 
 0.818
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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