STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
XF_0189Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Similar to SP|P22805 (percent identity: 47 %/query alignment coverage: 93.8 %/subject alignment coverage: 100.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (486 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.997
bioF
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
 
 
 0.989
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.986
XF_0190
Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
     
 0.840
cysQ
Sulfite synthesis pathway protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family.
 
     0.729
XF_0188
Conserved hypothetical protein; Similar to SP|P45799 (percent identity: 46 %/query alignment coverage: 95.7 %/subject alignment coverage: 95.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 75.
       0.694
bioC
Biotin synthesis protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
 
  
 0.672
XF_0186
Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
       0.644
XF_1796
Similar to SP|P06709 (percent identity: 40 %/query alignment coverage: 95.9 %/subject alignment coverage: 94.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.635
bioH
Biotin biosynthesis protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
 
  
 0.608
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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