STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XF_01936-pyruvoyl tetrahydrobiopterin synthase; Similar to SP|Q46903 (percent identity: 63 %/query alignment coverage: 93.5 %/subject alignment coverage: 95.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. (123 aa)    
Predicted Functional Partners:
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.991
folE
GTP cyclohydrolase I; Similar to SP|Q54769 (percent identity: 52 %/query alignment coverage: 95.1 %/subject alignment coverage: 91.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.977
queC
Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.941
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
 0.930
XF_0657
Alkaline phosphatase; Similar to SP|P00634 (percent identity: 32 %/query alignment coverage: 65.1 %/subject alignment coverage: 79.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the alkaline phosphatase family.
     
  0.900
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
  
  
 0.888
XF_1540
Transcriptional regulator (Crp/Fnr family); Similar to SP|P22260 (percent identity: 85 %/query alignment coverage: 100.4 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 210.
   
  0.740
hisI
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Similar to SP|O24714 (percent identity: 56 %/query alignment coverage: 93.7 %/subject alignment coverage: 97.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; In the C-terminal section; belongs to the PRA-PH family.
     
 0.635
XF_0192
ATP-dependent RNA helicase; Similar to SP|P25888 (percent identity: 52 %/query alignment coverage: 96.4 %/subject alignment coverage: 94.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the DEAD box helicase family.
       0.580
queA
S-adenosylmethionine: tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
     
 0.471
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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