Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trpCIndole-3-glycerol phosphate synthase; Similar to SP|P20577 (percent identity: 63 %/query alignment coverage: 99.2 %/subject alignment coverage: 94.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the TrpC family. (264 aa)    
Predicted Functional Partners:
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
 0.999
trpF
N-(5'-phosphoribosyl) anthranilate isomerase; Similar to SP|Q59649 (percent identity: 43 %/query alignment coverage: 89.1 %/subject alignment coverage: 96.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the TrpF family.
 
 0.999
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
 0.999
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
 
 0.999
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 0.994
XF_0211
Anthranilate synthase component II; Similar to SP|P00901 (percent identity: 67 %/query alignment coverage: 99.0 %/subject alignment coverage: 97.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 0.994
XF_1915
Anthranilate synthase component II; Similar to SP|P00901 (percent identity: 43 %/query alignment coverage: 92.8 %/subject alignment coverage: 97.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 0.986
XF_1914
Anthranilate synthase component I; Similar to SP|O66849 (percent identity: 37 %/query alignment coverage: 78.9 %/subject alignment coverage: 79.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
 0.958
XF_0674
Anthranilate synthase component I; Similar to SP|P05378 (percent identity: 36 %/query alignment coverage: 95.4 %/subject alignment coverage: 93.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -45.
 
 0.933
XF_0214
Conserved hypothetical protein; Similar to GI|987638 (percent identity: 27 %/query alignment coverage: 87.9 %/subject alignment coverage: 103.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
       0.835
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.