STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)    
Predicted Functional Partners:
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.999
panD
Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.998
coaX
Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family.
  
 
 0.951
cmk
Cytidylate kinase; Similar to SP|P43892 (percent identity: 48 %/query alignment coverage: 96.4 %/subject alignment coverage: 93.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
      0.905
XF_0149
DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.893
pgi
Glucose-6-phosphate isomerase; Similar to GI|2996048 (percent identity: 79 %/query alignment coverage: 99.6 %/subject alignment coverage: 89.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.727
XF_0228
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to SP|P43777 (percent identity: 50 %/query alignment coverage: 86.6 %/subject alignment coverage: 93.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.663
XF_1796
Similar to SP|P06709 (percent identity: 40 %/query alignment coverage: 95.9 %/subject alignment coverage: 94.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 0.649
pcnB
Polynucleotide adenyltransferase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.606
XF_0977
Malate oxidoreductase; Similar to SP|P43837 (percent identity: 57 %/query alignment coverage: 98.4 %/subject alignment coverage: 99.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 0.573
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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