STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiGlucose-6-phosphate isomerase; Similar to GI|2996048 (percent identity: 79 %/query alignment coverage: 99.6 %/subject alignment coverage: 89.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. (502 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.993
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.983
XF_0824
Pyruvate kinase type II; Similar to SP|P21599 (percent identity: 50 %/query alignment coverage: 95.8 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the pyruvate kinase family.
 
 
 0.977
XF_1936
Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.972
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.968
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 0.967
XF_0457
Glyceraldehyde-3-phosphate dehydrogenase; Similar to SP|P06977 (percent identity: 68 %/query alignment coverage: 97.9 %/subject alignment coverage: 98.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -63; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.960
pgk
Phosphoglycerate kinase; Similar to SP|P11665 (percent identity: 60 %/query alignment coverage: 78.0 %/subject alignment coverage: 100.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the phosphoglycerate kinase family.
 
 
 0.959
XF_0259
Phosphomannose isomerase-GDP-mannose pyrophosphorylase; Similar to SP|P29956 (percent identity: 84 %/query alignment coverage: 96.9 %/subject alignment coverage: 100.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.952
gpmA
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 
 0.930
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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