Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XF_0451Conserved hypothetical protein; Similar to SP|P26646 (percent identity: 40 %/query alignment coverage: 88.7 %/subject alignment coverage: 99.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. (363 aa)    
Predicted Functional Partners:
acsA
Acetyl coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.910
XF_0450
Two-component system, regulatory protein; Similar to SP|P43501 (percent identity: 50 %/query alignment coverage: 90.9 %/subject alignment coverage: 99.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -12.
     
 0.690
XF_2156
Protein phosphatase; Similar to GI|2337805 (percent identity: 35 %/query alignment coverage: 98.3 %/subject alignment coverage: 92.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
    
   0.686
XF_1212
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
    
   0.660
XF_0287
Regulator of pathogenicity factors; Similar to GI|1922920 (percent identity: 72 %/query alignment coverage: 98.4 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
   
 
 0.623
XF_2276
Peptide synthase; Similar to GI|2808752 (percent identity: 26 %/query alignment coverage: 100.0 %/subject alignment coverage: 105.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
   
 
 0.623
XF_0452
Integral membrane protease; HflC and HflK could encode or regulate a protease.
   
   0.569
XF_0453
Integral membrane proteinase; HflC and HflK could regulate a protease.
   
   0.569
XF_0278
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
    
   0.568
kdkA
Conserved hypothetical protein; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.
    
   0.568
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: low (26%) [HD]