STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nnrEConserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] (473 aa)    
Predicted Functional Partners:
XF_0758
Conserved hypothetical protein; Similar to SP|P31805 (percent identity: 43 %/query alignment coverage: 88.3 %/subject alignment coverage: 93.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
 
 0.949
rppH
Conserved hypothetical protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
 0.880
XF_1262
7,8-dihydro-8-oxoguanine-triphosphatase; Similar to SP|P41354 (percent identity: 38 %/query alignment coverage: 81.0 %/subject alignment coverage: 88.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 0.880
XF_2008
Conserved hypothetical protein; Similar to GI|4981730 (percent identity: 39 %/query alignment coverage: 68.7 %/subject alignment coverage: 83.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 0.880
XF_0192
ATP-dependent RNA helicase; Similar to SP|P25888 (percent identity: 52 %/query alignment coverage: 96.4 %/subject alignment coverage: 94.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the DEAD box helicase family.
  
 0.813
deaD
ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
  
 0.813
rhlB
ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily.
  
 0.813
XF_0759
N-acetylmuramoyl-L-alanine amidase precursor; Similar to SP|Q46929 (percent identity: 45 %/query alignment coverage: 41.7 %/subject alignment coverage: 54.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.773
groL
60kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
   0.736
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
  
 0.708
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.