Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
XF_0782Conserved hypothetical protein; Similar to GI|1673304 (percent identity: 35 %/query alignment coverage: 89.3 %/subject alignment coverage: 94.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. (75 aa)    
Predicted Functional Partners:
thiG
Thiamine biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.997
thiC
Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.930
XF_0466
Molybdopterin biosynthesis protein; Similar to GI|2983752 (percent identity: 53 %/query alignment coverage: 70.2 %/subject alignment coverage: 98.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.914
thiE
Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.889
XF_0621
Phosphomethylpyrimidine kinase; Similar to GI|3257572 (percent identity: 45 %/query alignment coverage: 92.3 %/subject alignment coverage: 56.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 0.845
XF_1120
Bifunctional DGTP-pyrophosphohydrolase/thiamine phosphate synthase; Similar to GI|1742868 (percent identity: 43 %/query alignment coverage: 38.4 %/subject alignment coverage: 91.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the Nudix hydrolase family.
 
  
 0.843
trmB
Conserved hypothetical protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
       0.772
XF_2041
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
    0.671
XF_0785
Sulfur deprivation response regulator; Similar to SP|Q39593 (percent identity: 22 %/query alignment coverage: 95.6 %/subject alignment coverage: 101.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
       0.649
XF_0781
Lipase/esterase; Similar to GI|2218156 (percent identity: 25 %/query alignment coverage: 102.5 %/subject alignment coverage: 94.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
     0.608
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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