| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XF_0884 | XF_2230 | XF_0884 | XF_2230 | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin binding protein 6 precursor; Similar to SP|P08506 (percent identity: 47 %/query alignment coverage: 90.2 %/subject alignment coverage: 89.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the peptidase S11 family. | 0.936 |
| XF_0884 | ftsI | XF_0884 | XF_0792 | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.993 |
| XF_0884 | ftsQ | XF_0884 | XF_0800 | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.516 |
| XF_0884 | ftsW | XF_0884 | XF_0796 | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.637 |
| XF_0884 | mrcA | XF_0884 | XF_0368 | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.942 |
| XF_0884 | mtgA | XF_0884 | XF_1715 | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.927 |
| XF_0884 | murF | XF_0884 | XF_0794 | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.522 |
| XF_0884 | murG | XF_0884 | XF_0797 | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.464 |
| XF_2230 | XF_0884 | XF_2230 | XF_0884 | Penicillin binding protein 6 precursor; Similar to SP|P08506 (percent identity: 47 %/query alignment coverage: 90.2 %/subject alignment coverage: 89.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the peptidase S11 family. | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.936 |
| XF_2230 | ftsI | XF_2230 | XF_0792 | Penicillin binding protein 6 precursor; Similar to SP|P08506 (percent identity: 47 %/query alignment coverage: 90.2 %/subject alignment coverage: 89.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the peptidase S11 family. | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.947 |
| XF_2230 | mrcA | XF_2230 | XF_0368 | Penicillin binding protein 6 precursor; Similar to SP|P08506 (percent identity: 47 %/query alignment coverage: 90.2 %/subject alignment coverage: 89.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the peptidase S11 family. | Penicillin binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.928 |
| XF_2230 | mtgA | XF_2230 | XF_1715 | Penicillin binding protein 6 precursor; Similar to SP|P08506 (percent identity: 47 %/query alignment coverage: 90.2 %/subject alignment coverage: 89.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the peptidase S11 family. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.919 |
| ftsI | XF_0884 | XF_0792 | XF_0884 | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.993 |
| ftsI | XF_2230 | XF_0792 | XF_2230 | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin binding protein 6 precursor; Similar to SP|P08506 (percent identity: 47 %/query alignment coverage: 90.2 %/subject alignment coverage: 89.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the peptidase S11 family. | 0.947 |
| ftsI | ftsL | XF_0792 | XF_0791 | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.993 |
| ftsI | ftsQ | XF_0792 | XF_0800 | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.992 |
| ftsI | ftsW | XF_0792 | XF_0796 | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.998 |
| ftsI | mrcA | XF_0792 | XF_0368 | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.961 |
| ftsI | mtgA | XF_0792 | XF_1715 | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.954 |
| ftsI | murE | XF_0792 | XF_0793 | Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.988 |
