STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nrdRConserved hypothetical protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (181 aa)    
Predicted Functional Partners:
XF_0950
Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.803
XF_0947
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
       0.682
ribB
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.635
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.611
nusB
Transcription termination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
 
   
 0.579
XF_1252
Conserved hypothetical protein; Protects the bacterial cell from host peptidases. Belongs to the protease inhibitor I39 (alpha-2- macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.
    
   0.570
nadE
NH3-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
   
 0.550
XF_0949
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
       0.517
XF_1796
Similar to SP|P06709 (percent identity: 40 %/query alignment coverage: 95.9 %/subject alignment coverage: 94.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
      
 0.482
XF_2419
Riboflavin biosynthesis protein; Similar to SP|P08391 (percent identity: 43 %/query alignment coverage: 91.7 %/subject alignment coverage: 92.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the ribF family.
   
  
 0.471
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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