Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ribBGTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (377 aa)    
Predicted Functional Partners:
XF_0950
Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 0.999
XF_0952
Riboflavin synthase alpha chain; Similar to SP|P51961 (percent identity: 45 %/query alignment coverage: 98.0 %/subject alignment coverage: 89.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -63.
 
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
 
 
 0.999
ribA
Riboflavin biosynthesis protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 0.990
folE
GTP cyclohydrolase I; Similar to SP|Q54769 (percent identity: 52 %/query alignment coverage: 95.1 %/subject alignment coverage: 91.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.947
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
 0.919
nusB
Transcription termination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
   
 
 0.894
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.857
rpsB
30S ribosomal protein S2; Similar to SP|P34831 (percent identity: 60 %/query alignment coverage: 93.2 %/subject alignment coverage: 98.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 222; Belongs to the universal ribosomal protein uS2 family.
   
  
 0.843
XF_1748
5-amino-6-(5-phosphoribosylamino)uracil reductase; Similar to SP|Q58085 (percent identity: 21 %/query alignment coverage: 92.0 %/subject alignment coverage: 97.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.836
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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