STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
asdaspartate-B-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)    
Predicted Functional Partners:
XF_2225
Bifunctional aspartokinase/homoserine dehydrogenase I; Similar to SP|P00561 (percent identity: 40 %/query alignment coverage: 98.4 %/subject alignment coverage: 99.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -126; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.996
XF_1116
Bifunctional diaminopimelate decarboxylase/aspartate kinase; Similar to SP|P00861 (percent identity: 33 %/query alignment coverage: 43.4 %/subject alignment coverage: 89.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
 
 
 0.991
dapA
Dihydroxydipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.977
XF_1372
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 0.768
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
  
 0.667
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
  
 0.665
trpF
N-(5'-phosphoribosyl) anthranilate isomerase; Similar to SP|Q59649 (percent identity: 43 %/query alignment coverage: 89.1 %/subject alignment coverage: 96.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the TrpF family.
     
 0.652
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
  
 0.651
XF_2710
Glutamate synthase, alpha subunit; Similar to SP|P09831 (percent identity: 53 %/query alignment coverage: 99.7 %/subject alignment coverage: 97.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -117.
  
  
 0.628
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
  
 0.618
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: low (24%) [HD]