Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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XF_1402Phosphotransferase system enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (590 aa)    
Predicted Functional Partners:
ptsH
Phosphotransferase system HPr enzyme; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.
 
 0.999
hprK
HPr kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
   
 0.889
XF_1404
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
   
 0.857
XF_1407
Sigma-54 modulation protein; Similar to SP|P17160 (percent identity: 44 %/query alignment coverage: 81.0 %/subject alignment coverage: 87.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 0.610
XF_1405
Conserved hypothetical protein; Displays ATPase and GTPase activities.
     
 0.563
XF_1408
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.495
XF_1401
Mg++ transporter; Similar to GI|1652477 (percent identity: 26 %/query alignment coverage: 102.9 %/subject alignment coverage: 61.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -132.
       0.476
pgk
Phosphoglycerate kinase; Similar to SP|P11665 (percent identity: 60 %/query alignment coverage: 78.0 %/subject alignment coverage: 100.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the phosphoglycerate kinase family.
   
  
 0.472
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
      
 0.466
nuoB
NADH-ubiquinone oxidoreductase, NQO6 subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
   
    0.444
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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