STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XF_1412Conserved hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (182 aa)    
Predicted Functional Partners:
XF_1413
Polysialic acid capsule expression protein; Similar to GI|2983910 (percent identity: 45 %/query alignment coverage: 96.7 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 36.
  
 0.989
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Similar to SP|P17579 (percent identity: 44 %/query alignment coverage: 94.6 %/subject alignment coverage: 98.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the KdsA family.
  
 0.986
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.977
lptC
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
  
  
 0.913
XF_1409
ABC transporter ATP-binding protein; Similar to SP|P45073 (percent identity: 60 %/query alignment coverage: 100.0 %/subject alignment coverage: 99.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
  
 0.859
lptA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
  
    0.825
XF_1408
RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
       0.682
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.614
XF_1414
Conserved hypothetical protein; Similar to SP|P73055 (percent identity: 38 %/query alignment coverage: 96.0 %/subject alignment coverage: 84.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the BolA/IbaG family.
       0.590
XF_1407
Sigma-54 modulation protein; Similar to SP|P17160 (percent identity: 44 %/query alignment coverage: 81.0 %/subject alignment coverage: 87.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
       0.543
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.