STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa)    
Predicted Functional Partners:
guaA
Glutamine amidotransferase; Catalyzes the synthesis of GMP from XMP.
 
 
 0.963
XF_2354
Hypoxanthine-guanine phosphoribosyltransferase; Similar to SP|Q02522 (percent identity: 27 %/query alignment coverage: 91.9 %/subject alignment coverage: 92.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
   
 
 0.920
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 0.919
XF_1553
Adenylosuccinate lyase; Similar to SP|P44797 (percent identity: 57 %/query alignment coverage: 83.8 %/subject alignment coverage: 97.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
 0.919
surE
Survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
  
  
  0.915
XF_0352
Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.914
XF_0560
GMP synthase; Similar to GI|6448738 (percent identity: 37 %/query alignment coverage: 90.8 %/subject alignment coverage: 93.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.910
XF_1197
Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
   
 
 0.902
XF_1196
Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.901
XF_0186
Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
  0.900
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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