STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XF_1553Adenylosuccinate lyase; Similar to SP|P44797 (percent identity: 57 %/query alignment coverage: 83.8 %/subject alignment coverage: 97.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (532 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.998
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP|P43851 (percent identity: 53 %/query alignment coverage: 97.1 %/subject alignment coverage: 97.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the SAICAR synthetase family.
  
 0.996
purH
Bifunctional purine biosynthesis protein; Similar to SP|P15639 (percent identity: 59 %/query alignment coverage: 91.3 %/subject alignment coverage: 99.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 0.995
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 0.988
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.962
purD
Glycinamide ribonucleotide synthetase; Similar to SP|P26977 (percent identity: 64 %/query alignment coverage: 97.7 %/subject alignment coverage: 99.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.960
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
  
  
 0.950
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
  
 0.950
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 0.945
surE
Survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
    
 0.917
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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