STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
folEGTP cyclohydrolase I; Similar to SP|Q54769 (percent identity: 52 %/query alignment coverage: 95.1 %/subject alignment coverage: 91.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. (206 aa)    
Predicted Functional Partners:
XF_0193
6-pyruvoyl tetrahydrobiopterin synthase; Similar to SP|Q46903 (percent identity: 63 %/query alignment coverage: 93.5 %/subject alignment coverage: 95.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.977
XF_0091
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
 0.975
ribA
Riboflavin biosynthesis protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 
 
 
 0.971
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
     
 0.959
ribB
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
 
 0.947
XF_0436
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
  
 0.936
XF_0228
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to SP|P43777 (percent identity: 50 %/query alignment coverage: 86.6 %/subject alignment coverage: 93.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
  
 0.934
XF_0657
Alkaline phosphatase; Similar to SP|P00634 (percent identity: 32 %/query alignment coverage: 65.1 %/subject alignment coverage: 79.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the alkaline phosphatase family.
     
  0.900
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
  0.820
XF_1456
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Similar to SP|P72736 (percent identity: 35 %/query alignment coverage: 77.5 %/subject alignment coverage: 83.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
  
 0.812
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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