node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XF_0186 | XF_0352 | XF_0186 | XF_0352 | Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.910 |
XF_0186 | XF_1316 | XF_0186 | XF_1316 | Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | ATP:GTP 3'-pyrophosphotranferase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.910 |
XF_0186 | folE | XF_0186 | XF_1983 | Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | GTP cyclohydrolase I; Similar to SP|Q54769 (percent identity: 52 %/query alignment coverage: 95.1 %/subject alignment coverage: 91.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | 0.817 |
XF_0186 | folE2 | XF_0186 | XF_2096 | Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
XF_0186 | ndk | XF_0186 | XF_0458 | Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
XF_0186 | ribA | XF_0186 | XF_1992 | Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | Riboflavin biosynthesis protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.800 |
XF_0186 | ribB | XF_0186 | XF_0953 | Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.822 |
XF_0352 | XF_0186 | XF_0352 | XF_0186 | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | 0.910 |
XF_0352 | XF_1316 | XF_0352 | XF_1316 | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | ATP:GTP 3'-pyrophosphotranferase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.920 |
XF_0352 | folE | XF_0352 | XF_1983 | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase I; Similar to SP|Q54769 (percent identity: 52 %/query alignment coverage: 95.1 %/subject alignment coverage: 91.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | 0.800 |
XF_0352 | folE2 | XF_0352 | XF_2096 | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
XF_0352 | ndk | XF_0352 | XF_0458 | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.907 |
XF_0352 | ribA | XF_0352 | XF_1992 | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Riboflavin biosynthesis protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.803 |
XF_0352 | ribB | XF_0352 | XF_0953 | Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.825 |
XF_0950 | XF_0952 | XF_0950 | XF_0952 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase alpha chain; Similar to SP|P51961 (percent identity: 45 %/query alignment coverage: 98.0 %/subject alignment coverage: 89.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -63. | 0.999 |
XF_0950 | folE | XF_0950 | XF_1983 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase I; Similar to SP|Q54769 (percent identity: 52 %/query alignment coverage: 95.1 %/subject alignment coverage: 91.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. | 0.422 |
XF_0950 | ribA | XF_0950 | XF_1992 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.995 |
XF_0950 | ribB | XF_0950 | XF_0953 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
XF_0950 | ribH | XF_0950 | XF_0954 | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.977 |
XF_0952 | XF_0950 | XF_0952 | XF_0950 | Riboflavin synthase alpha chain; Similar to SP|P51961 (percent identity: 45 %/query alignment coverage: 98.0 %/subject alignment coverage: 89.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -63. | Riboflavin-specific deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |