STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XF_1999Branched-chain amino acid aminotransferase; Similar to SP|Q10399 (percent identity: 55 %/query alignment coverage: 100.3 %/subject alignment coverage: 98.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder. (362 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.992
ilvD
Dihydroxy-acid dehydratase; Similar to SP|P44851 (percent identity: 73 %/query alignment coverage: 100.3 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -78; Belongs to the IlvD/Edd family.
  
 0.975
XF_1819
Threonine dehydratase catabolic; Similar to SP|P05792 (percent identity: 39 %/query alignment coverage: 82.9 %/subject alignment coverage: 95.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 0.932
XF_0864
Cystathionine gamma-synthase; Similar to SP|P00935 (percent identity: 57 %/query alignment coverage: 93.1 %/subject alignment coverage: 97.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 0.931
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     
 0.929
XF_2225
Bifunctional aspartokinase/homoserine dehydrogenase I; Similar to SP|P00561 (percent identity: 40 %/query alignment coverage: 98.4 %/subject alignment coverage: 99.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -126; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.924
XF_2396
Aminotransferase; Similar to SP|O33267 (percent identity: 45 %/query alignment coverage: 91.3 %/subject alignment coverage: 90.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
 
 0.921
XF_1428
Glutamate-cysteine ligase precursor; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
     
  0.900
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.821
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.660
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.