STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XF_2012Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (99 aa)    
Predicted Functional Partners:
XF_2011
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
    0.946
ihfA
Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
    0.782
XF_1957
TonB protein; Similar to GI|3978235 (percent identity: 26 %/query alignment coverage: 67.6 %/subject alignment coverage: 78.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
    0.763
ftsL
Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
   
 0.750
XF_2009
Similar to GI|1653657 (percent identity: 46 %/query alignment coverage: 98.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -75.
 
   
 0.720
XF_2010
Conserved hypothetical protein; Similar to GI|140683 (percent identity: 36 %/query alignment coverage: 91.4 %/subject alignment coverage: 87.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the UPF0149 family.
 
  
 0.718
zipA
Cell division protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
 
   
 0.671
XF_1997
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
     0.669
XF_1372
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
     0.651
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.639
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.