STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE2Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (299 aa)    
Predicted Functional Partners:
XF_0193
6-pyruvoyl tetrahydrobiopterin synthase; Similar to SP|Q46903 (percent identity: 63 %/query alignment coverage: 93.5 %/subject alignment coverage: 95.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
    
 0.917
folE
GTP cyclohydrolase I; Similar to SP|Q54769 (percent identity: 52 %/query alignment coverage: 95.1 %/subject alignment coverage: 91.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.913
ribB
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
 0.903
XF_0657
Alkaline phosphatase; Similar to SP|P00634 (percent identity: 32 %/query alignment coverage: 65.1 %/subject alignment coverage: 79.6 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the alkaline phosphatase family.
     
  0.900
ribA
Riboflavin biosynthesis protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
  0.900
XF_2095
Carbonic anhydrase; Similar to SP|P40881 (percent identity: 32 %/query alignment coverage: 99.5 %/subject alignment coverage: 85.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
    0.815
XF_0824
Pyruvate kinase type II; Similar to SP|P21599 (percent identity: 50 %/query alignment coverage: 95.8 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the pyruvate kinase family.
    
  0.808
XF_0186
Conserved hypothetical protein; Similar to SP|P33646 (percent identity: 42 %/query alignment coverage: 94.9 %/subject alignment coverage: 100.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
  0.800
XF_0352
Pentaphosphate guanosine-3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.800
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.800
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.