STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mtnBConserved hypothetical protein; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (218 aa)    
Predicted Functional Partners:
mtnC
Enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
 
 0.998
mtnA
Initiation factor eIF-2B, alpha subunit-related; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
 0.992
mtnD
Dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
 
  
 0.987
XF_2208
Cationic amino acid transporter; Similar to GI|3169028 (percent identity: 41 %/query alignment coverage: 102.3 %/subject alignment coverage: 97.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.833
XF_2207
Cationic amino acid transporter; Similar to GI|3169028 (percent identity: 43 %/query alignment coverage: 103.1 %/subject alignment coverage: 99.0 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.691
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
  
 0.688
XF_2212
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.617
speD
S-adenosyl methionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
     
 0.572
XF_2225
Bifunctional aspartokinase/homoserine dehydrogenase I; Similar to SP|P00561 (percent identity: 40 %/query alignment coverage: 98.4 %/subject alignment coverage: 99.4 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: -126; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
  
 0.551
XF_2206
D-3-phosphoglycerate dehydrogenase; Similar to SP|P08328 (percent identity: 62 %/query alignment coverage: 99.0 %/subject alignment coverage: 99.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
    0.526
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.