Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XF_2230Penicillin binding protein 6 precursor; Similar to SP|P08506 (percent identity: 47 %/query alignment coverage: 90.2 %/subject alignment coverage: 89.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the peptidase S11 family. (396 aa)    
Predicted Functional Partners:
ftsI
Penicillin binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
 
 0.947
mrdA
Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 
 0.946
XF_1614
Penicillin binding protein; Similar to SP|P39844 (percent identity: 39 %/query alignment coverage: 99.6 %/subject alignment coverage: 100.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.944
XF_0884
Penicillin binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
   
 
 0.936
mrcA
Penicillin binding protein 1A; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.928
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
   
 
 0.919
XF_0881
Hypothetical protein; identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 75.
     
 0.911
XF_2235
Bifunctional penicillin binding protein 1C precursor; Similar to SP|P76577 (percent identity: 47 %/query alignment coverage: 97.9 %/subject alignment coverage: 101.2 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
     
 0.901
XF_1309
Rod shape-determining protein; Similar to SP|P13519 (percent identity: 77 %/query alignment coverage: 93.8 %/subject alignment coverage: 99.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
  
 0.478
mrdB
Rod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
   
 0.476
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
Server load: medium (50%) [HD]