STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
XF_2595Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (118 aa)    
Predicted Functional Partners:
XF_1196
Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.968
XF_2394
Glutaredoxin-like protein; Similar to GI|3650389 (percent identity: 54 %/query alignment coverage: 26.2 %/subject alignment coverage: 29.9 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
 
 0.895
secB
Protein-export protein; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.813
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
  
 
 0.793
XF_2669
Conserved hypothetical protein; Similar to SP|P37010 (percent identity: 47 %/query alignment coverage: 95.2 %/subject alignment coverage: 86.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.693
nfuA
Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
  
 0.627
XF_2593
Two-component system, regulatory protein; Similar to SP|P08402 (percent identity: 56 %/query alignment coverage: 84.2 %/subject alignment coverage: 97.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 57.
       0.614
XF_2594
Conserved hypothetical protein; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state.
       0.595
atpF
ATP synthase, B chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
    0.589
XF_1800
Conserved hypothetical protein; Similar to SP|P37688 (percent identity: 38 %/query alignment coverage: 88.2 %/subject alignment coverage: 99.3 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
  
  
 0.558
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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