STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (393 aa)    
Predicted Functional Partners:
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
 0.999
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP|P43851 (percent identity: 53 %/query alignment coverage: 97.1 %/subject alignment coverage: 97.7 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the SAICAR synthetase family.
  
 0.996
purM
5'-phosphoribosyl-5-aminoimidazole synthetase; Similar to SP|P08178 (percent identity: 59 %/query alignment coverage: 97.4 %/subject alignment coverage: 99.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder/Start codon shift: 117.
 
 
 0.996
purL
Phosphoribosylformylglycinamidine synthetase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.996
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.995
purN
5'-phosphoribosylglycinamide transformylase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.994
XF_1553
Adenylosuccinate lyase; Similar to SP|P44797 (percent identity: 57 %/query alignment coverage: 83.8 %/subject alignment coverage: 97.8 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.993
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.980
purH
Bifunctional purine biosynthesis protein; Similar to SP|P15639 (percent identity: 59 %/query alignment coverage: 91.3 %/subject alignment coverage: 99.1 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
  
 0.968
purD
Glycinamide ribonucleotide synthetase; Similar to SP|P26977 (percent identity: 64 %/query alignment coverage: 97.7 %/subject alignment coverage: 99.5 %); identified by sequence similarity; putative; ORF located using Glimmer/RBSfinder.
 
  
 0.953
Your Current Organism:
Xylella fastidiosa
NCBI taxonomy Id: 160492
Other names: X. fastidiosa 9a5c, Xylella fastidiosa 9a5c
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