Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nfoDeoxyribonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (375 aa)    
Predicted Functional Partners:
AIQ59007.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.927
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 
 0.831
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.790
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
   
 
 0.788
AIQ58334.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.778
AIQ56735.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.731
AIQ56734.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.683
AIQ60393.1
Single-stranded DNA exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.621
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.584
AIQ55786.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.540
Your Current Organism:
Paenibacillus borealis
NCBI taxonomy Id: 160799
Other names: CCUG 43137, CIP 107056, DSM 13188, Paenibacillus borealis Elo et al. 2001, strain KK19
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