STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIQ57416.1Pyrimidine reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.748
AIQ59414.1
Prevent-host-death protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.694
AIQ59462.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.662
AIQ57750.1
Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
  
 
 0.601
AIQ60369.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.541
AIQ58253.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.535
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
  
 0.528
AIQ55701.1
3-demethylubiquinone-9 3-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.523
AIQ57254.1
Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.512
AIQ59455.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.507
Your Current Organism:
Paenibacillus borealis
NCBI taxonomy Id: 160799
Other names: CCUG 43137, CIP 107056, DSM 13188, Paenibacillus borealis Elo et al. 2001, strain KK19
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