Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIQ58390.13-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)    
Predicted Functional Partners:
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.941
cysI
Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 0.933
AIQ60249.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.925
AIQ60353.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.925
AIQ59425.1
Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
     
 0.921
AIQ55954.1
FMN reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.911
AIQ56619.1
Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.908
ldh
Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
 
  0.905
ldh-2
Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 
  0.905
AIQ57660.1
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.901
Your Current Organism:
Paenibacillus borealis
NCBI taxonomy Id: 160799
Other names: CCUG 43137, CIP 107056, DSM 13188, Paenibacillus borealis Elo et al. 2001, strain KK19
Server load: low (30%) [HD]