| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AIQ55956.1 | folE | PBOR_02460 | PBOR_03175 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.802 |
| AIQ55956.1 | queE | PBOR_02460 | PBOR_19760 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.831 |
| AIQ58909.1 | folE | PBOR_19765 | PBOR_03175 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
| AIQ58909.1 | guaA | PBOR_19765 | PBOR_03345 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.466 |
| AIQ58909.1 | queC | PBOR_19765 | PBOR_19770 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.991 |
| AIQ58909.1 | queE | PBOR_19765 | PBOR_19760 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
| AIQ58909.1 | queF | PBOR_19765 | PBOR_19775 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.970 |
| AIQ61010.1 | queE | PBOR_31945 | PBOR_19760 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.461 |
| folE | AIQ55956.1 | PBOR_03175 | PBOR_02460 | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.802 |
| folE | AIQ58909.1 | PBOR_03175 | PBOR_19765 | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
| folE | queE | PBOR_03175 | PBOR_19760 | GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.633 |
| guaA | AIQ58909.1 | PBOR_03345 | PBOR_19765 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.466 |
| guaA | purF | PBOR_03345 | PBOR_03485 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.799 |
| guaA | queE | PBOR_03345 | PBOR_19760 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.478 |
| guaA | queF | PBOR_03345 | PBOR_19775 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.537 |
| purF | guaA | PBOR_03485 | PBOR_03345 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.799 |
| purF | queE | PBOR_03485 | PBOR_19760 | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.422 |
| queC | AIQ58909.1 | PBOR_19770 | PBOR_19765 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
| queC | queE | PBOR_19770 | PBOR_19760 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
| queC | queF | PBOR_19770 | PBOR_19775 | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.998 |