STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKS50464.1Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
   0.629
dltC
Cytochrome C552; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
  
 
 0.606
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.606
AKS50465.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.548
AKS50485.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.528
AKS51193.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.528
AKS51294.1
Nucleoside-diphosphate-sugar epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.528
AKS51309.1
NmrA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.528
AKS52134.1
NmrA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.528
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.414
Your Current Organism:
Lactobacillus farciminis
NCBI taxonomy Id: 1612
Other names: ATCC 29644, BCRC 14043, CCUG 30671, CIP 103136, DSM 20184, KCTC 3681, L. farciminis, LMG 9200, LMG:9200, Lactobacillus sp. S215, NCIMB 11717, NRRL B-4566
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